Immuno-Oncology Registry

Our consortium's multidisciplinary team of clinicians and informaticians designed and built a centralized research data warehouse for ImmunoOncology that is enabling novel hypothesis generation and retrospective outcomes research at the 10 DC-Baltimore based MedStar Health network hospitals and Hackensack Meridian Health system in New Jersey. 

Data sources include hospital medical records, Labs, pathology, radiology, and Cancer Registry data. Data was extracted from different hospital systems and integrated into the I/O registry to allow clinicians to capture additional data from patient charts. 

Our integrative approach helps assess outcomes in patients with different commodities across all hospitals, effects of treatment with steroids on immune toxicities and their outcomes, use of various drugs before and during Immuno-Oncology treatment and their impact on outcomes and toxicities. 

Toxicities and adverse events data in EHRs is not comprehensive. Hence, in addition to data extracted using ICD codes from structured fields/tables, we are using our in house developed NLP methodologies to automatically identify toxicities in patient charts.